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Desperate for rent money, supermarket clerk Ronna (Sarah Polley, Dawn of the Dead) agrees to broker a drug deal that quickly spirals out of control. Elsewhere, two soap opera actors (Jay Mohr and Scott Wolf) become entangled with an unnervingly friendly narcotics detective (William Fichtner), while a Vegas road trip involving Ronna's coworker Simon (Desmond Askew) erupts into sex, violence and utter mayhem. As the stories collide, every bad choice pushes the night closer to catastrophe.